VIDEO
HIGHLIGHT
Log InSign up
10.Impacto de la información generada: Uso de herramientas tecnológicas para la vigilancia de la RAM
SummaryTranscriptChat

10.Impacto de la información generada: Uso de herramientas tecnológicas para la vigilancia de la RAM

Antimicrobial Resistance: Key Insights and Strategies

Introduction to Antimicrobial Resistance

  • The course aims to summarize significant learnings regarding antimicrobial resistance, emphasizing the incorporation of these principles into surveillance and research activities.

Importance of Antibiotics

  • Antibiotics are essential medications with a wide range of applications, including treating bacterial infections, preventing surgical infections, and aiding immunocompromised patients.

Global Challenge of Antimicrobial Resistance

  • Preventing a future without antibiotics is crucial for global public health; this challenge is one of humanity's greatest in the current century.
  • In 2015, all countries signed a global agreement proposed by the World Health Organization (WHO) to combat antimicrobial resistance.

Surveillance and Research Significance

  • Surveillance research provides critical information for decision-making in various areas, particularly in therapeutic contexts to guide treatment against resistant bacterial infections.
  • Identifying resistance mechanisms and their dissemination is vital for advancing containment strategies against antimicrobial resistance.

Case Studies on Regulation Changes

  • Research in animal production has led many countries to prohibit antibiotics as growth promoters due to associated risks.
  • Excessive antibiotic use in human medicine correlates with emerging resistant strains; thus, stricter regulations on prescription practices are necessary.

Regional Actions Against Antibiotic Use

  • Countries like Argentina, Colombia, Ecuador, and Uruguay have banned colistin use in aquaculture to protect public health since it is deemed critically important by WHO.

Patterns of Dissemination

  • Surveillance helps identify temporal-spatial patterns of gene dissemination related to resistance and multi-resistant bacteria phenotypes.

Priority Bacterial Species

  • The WHO identifies several priority bacterial species posing threats globally. Notable examples include:
  • Gram-negative: E. coli, Klebsiella pneumoniae, Salmonella spp., Neisseria gonorrhoeae
  • Gram-positive: Staphylococcus aureus, Streptococcus pneumoniae

Collaborative Efforts Needed

  • There’s an evident need for collaboration among academic institutions and government sectors (healthcare, agriculture, environment), focusing on a One Health approach to tackle antimicrobial resistance effectively.

Institutional Framework for Collaboration

  • The tripartite collaboration between WHO, OIE (World Organisation for Animal Health), and FAO (Food and Agriculture Organization of the United Nations) serves as a global reference point under the One Health framework.

Guidelines for Action

The Role of Environment in Antimicrobial Resistance

Environmental Impact on Antimicrobial Resistance

  • The environment serves as a reservoir and vehicle for the dissemination of antimicrobial resistance, highlighting the need for integrated surveillance strategies that adhere to a One Health approach.
  • Monitoring antimicrobial resistance in environmental samples is crucial for understanding its spread and developing effective containment strategies.

Importance of Public Access to Research Data

  • Emphasizing the necessity for public access to information generated from surveillance and research activities related to antimicrobial resistance.
  • Publicly accessible data promotes inter-institutional projects that are broader in scope and relevance, facilitating progress in combating antimicrobial resistance.

Global Databases Supporting Research

  • The establishment of large public databases, such as the National Database of Resistant Microorganisms (DARO), provides global insights into antimicrobial resistance across various countries.
  • These databases contain valuable information from nearly all continents, enhancing international collaboration and research efforts.

Tools for Studying Resistance Profiles

  • There are databases available that allow researchers to study resistance profiles and prioritize species, combined with user-friendly bioinformatics tools accessible to the public.
Playlists: CURSO - "Resistencia a los Antimicrobianos: Herramientas tecnológicas de vanguardia para su vigilancia"
Video description

Este es el décimo módulo del curso en línea generado por el Centro Colaborador en Resistencia Antimicrobiana en bacterias transmitidas por los alimentos y ambientales MEX-33 (https://apps.who.int/whocc/Detail.asp...) a cargo de la QBF Amada Vélez Méndez, Directora General de Inocuidad Agroalimentaria, Acuícola y Pesquera del Servicio Nacional de Sanidad, Inocuidad y Calidad Agroalimentaria (SENASICA) y la QA Mayrén Cristina Zamora Nava, Directora del Centro Nacional de Referencia de Plaguicidas y Contaminantes. El curso completo estará disponible en la plataforma de entrenamiento de la OPS/OMS y contará con actividades complementarias de reforzamiento en cada uno de los temas. En este módulo 10 se aborda: Resumen de los puntos importantes del curso como son el uso de antibióticos y prohibición como promotores de crecimiento, Plan de acción mundial sobre la resistencia a los antimicrobianos, el impacto de la información en la toma de decisiones considerando el enfoque de “Una Salud” y finalmente las bases de datos de RAM (NDARO y Resistome tracker)