¿Qué es la alergia?
What Causes Respiratory Allergies?
Overview of Respiratory Allergies
- Respiratory allergies typically cause symptoms affecting the nose, eyes, and throat when an allergic individual comes into contact with a harmless substance known as an allergen.
- These symptoms can disrupt daily life, leading to sleep disturbances, fatigue, absenteeism from work or school, and poor performance in various activities.
Mechanism of Allergic Reactions
- An allergy is characterized as an overreaction of the immune system upon encountering an allergen. This reaction occurs in two phases:
- Desensitization Phase: During initial contact with the allergen, the immune system identifies it as a threat. Macrophages and lymphocytes interact, producing specific antibodies that bind to mast cells.
- Reaction Phase: Upon subsequent exposure to the same allergen, sensitized mast cells recognize it immediately and release inflammatory substances that activate the immune response.
Symptoms and Progression
- The inflammatory molecules released are responsible for allergy symptoms. Respiratory allergies are chronic conditions that can worsen if left untreated.
- Patients sensitive to one allergen may develop sensitivities to additional allergens over time. For instance, allergic rhinitis can lead to further complications if not managed properly.