How a Low-Carb Diet Can Boost Exercise Performance and Health | Professor Tim Noakes & Josh Clemente
The Importance of Carbohydrate Titration for Metabolic Health
In this section, Professor Tim Noakes discusses the importance of carbohydrate titration for metabolic health and how excessive carbohydrate consumption can lead to diabetes.
Carbohydrate Titration for Metabolic Health
- To maintain metabolic health, it is important to titrate the amount of carbohydrates in your diet.
- Athletes who consume too much carbohydrate may become pre-diabetic or diabetic over time.
- Muscle glycogen depletion was once believed to cause fatigue during prolonged exercise, leading to a focus on consuming as many carbohydrates as possible.
Introduction and Recent Work on Low Carb High-Fat Diets
In this section, Professor Tim Noakes introduces himself and his work on low carb high-fat diets for recreational male athletes.
Introduction and Recent Work
- Professor Tim Noakes has spent decades studying metabolic health and fitness adaptation under different metabolic circumstances.
- His recent work focused on adapting to low carb high-fat diets for recreational male athletes.
- In 2010, he learned about the low carb diet and changed his approach after reading Eric Westman Jeff Erlick's book.
Hypoglycemia During Exercise
In this section, Professor Tim Noakes discusses hypoglycemia during exercise and how it led him to develop a product called FRN food Port ice Rose.
Hypoglycemia During Exercise
- Professor Tim Noakes' first study in sports science was on hypoglycemia during exercise.
- He believed that hypoglycemia developed during exercise and that carbohydrates were essential for exercise.
- Together with Bruce Fordyce, he developed a product called FRN food Port ice Rose, which was the first goo used during exercise.
Transition to Low Carb Diet
In this section, Professor Tim Noakes discusses his transition to a low carb diet and the challenges he faced.
Transition to Low Carb Diet
- In 2010, Professor Tim Noakes changed his approach after learning about the low carb diet and reading Eric Westman Jeff Erlick's book.
- He lost funding and faced criticism from his university for promoting a diet that had reversed type 2 diabetes.
- His type 2 diabetes eventually reversed, but he had to fight in court for four years to clear his name.
The Role of Muscle Glycogen During Exercise Performance
In this section, the speaker discusses the role of muscle glycogen during exercise performance and how it relates to carbohydrate and fat oxidation.
5K Time Trials and VO2 Max Testing
- The speaker's team conducted 5K time trials on treadmills to compare the results of high carb low-fat diets with low carb high-fat diets.
- They also looked at Jeff Ehrlich's research on VO2 max testing and the crossover point where more carbohydrates than fat are burned during exercise.
- Philip produced a paper showing that the crossover point shifted far to the right at about 85% VO2 max, which is when you're not meant to be burning any fat.
One Kilometer Time Trials
- The team conducted one kilometer time trials but found no difference in performance between high carb low-fat diets and low carb high-fat diets.
- However, they did find that athletes on a low-carb diet had enough glycogen for 1K.
- The team then decided to conduct six times eight hundred meter repetitions without measuring oxygen consumption or metabolism.
- Surprisingly, there was no difference in performance between the two groups even after several sprints.
Muscle Glycogen Obligatory Role During Exercise Performance
- Oxygen consumption and respiratory quotient were measured, which showed an increase in fat oxidation as repetitions increased.
- This contradicts traditional hypotheses that suggest that after three sprints, performance should decrease in athletes on a low-carb diet due to lack of glycogen.
- The highest rates of fat oxidation were observed at 86% VO2 max, which is the point where you're not meant to be burning any fat.
- The speaker argues that muscle glycogen doesn't have an obligatory role during exercise performance, even at high intensities.
Original Studies on Muscle Glycogen
- The Scandinavians conducted original studies in 1967 that showed low blood glucose levels at the point of exhaustion despite low muscle glycogen levels.
- Recent studies also show big differences in muscle glycogen and fat oxidation at exhaustion but no difference in blood glucose concentration.
The Importance of Blood Glucose in Exercise Performance
In this section, the speaker discusses the importance of blood glucose in exercise performance and how it differs from muscle glycogen.
Blood Glucose vs. Fat as Fuel Sources
- Burning carbohydrates during exercise makes you perform better.
- Carbohydrates help maintain blood glucose levels, which is important for brain function during exercise.
- The body can adapt to using fat as fuel at all intensities of exercise, not just low-intensity exercise.
- Blood glucose becomes the limiting factor during exercise when the muscles demand more glucose than the liver can provide.
Muscle Glycogen vs. Blood Glucose Regulation
- Muscle glycogen drops linearly during exercise, but blood glucose oxidation increases paradoxically.
- The regulation of muscle glycogen and blood glucose is different because they are not interchangeable fuels.
- When blood glucose levels drop, power output decreases and fatigue symptoms appear.
Implications for Exercise Performance
- Maintaining blood glucose levels is crucial for optimal exercise performance.
- The body burns glycogen instead of fat because it needs to maintain blood glucose levels for brain function.
The Body's Regulation of Blood Glucose Concentration
In this section, the speaker explains how the body regulates blood glucose concentration and why it burns glucose.
The First Rule in Metabolism
- The body regulates blood glucose concentration to keep it within a narrow band.
- When glucose goes out of its sink, the body responds dramatically to get it back into range.
- Dumping excess glucose into muscles is one way to quickly bring glucose levels back into range.
Burning Glucose vs. Burning Fat
- Muscles burn glucose when they have lots of it.
- Low-carb athletes burn more fat than carbohydrate during exercise.
- Muscle glycogen content determines how much fat and carbohydrate you burn.
Natural State of the Body
- People on low-carb diets burned more fat than those on high-carb diets in 1967 studies.
- Even non-fat-adapted athletes can burn fat without eating carbs.
- The natural state of the body may be fat oxidation rather than carbohydrate burning.
Why Glucose is Obligatory for the Body
In this section, the speaker explains why even in a highly fat-adapted state, there will always be circulating glucose in the bloodstream.
Obligatory Role of Glucose
- Glucose is obligatory for bodily functions, even in a highly fat-adapted state.
Glucose and Fat Oxidation
In this section, the speaker discusses the role of glucose and fat oxidation in the body.
Glucose as Brain Fuel
- The brain has a critical fuel dependency on glucose.
- Glucose will always be a critical element for brain fuel.
Fat Oxidation in Heart Muscle
- The muscle tissue in the heart almost exclusively oxidizes fat.
- The heart is hyper-flexible and can burn glucose, lactate, insulin, ketones or fats depending on what it is given.
Application to Different Athlete Groups
In this section, the speaker talks about how these findings apply to different groups of athletes.
Recreational Male Athletes
- Findings showed that recreational male athletes did not need to eat high carb diets to perform well.
- 88% of American runners could benefit from starting a low-carb diet based on these findings.
Elite Athletes
- Elliot Kipchoge only burns 2 grams of carbohydrate per minute when running a marathon due to his small size.
- No further information provided in transcript regarding elite athletes.
Female Athletes
- No information provided in transcript regarding female athletes.
The Flexibility of the Body to Perform on Different Diets
In this section, the speaker discusses how cattle wrestlers used to eat animal-based diets and only recently moved to high carbohydrate diets. He also talks about a study that showed carbohydrates ingested during exercise could improve performance.
Cattle Wrestlers and High Carbohydrate Diets
- Cattle wrestlers used to eat animal-based diets.
- A study showed that carbohydrates ingested during exercise could improve performance.
Fat Adaptation in Elite Cyclists
In this section, the speaker talks about a study that showed people eating a high carbohydrate diet could be fat adapted. He also discusses how cyclists are more likely to be fat adapted than runners due to their training.
Fat Adaptation in Elite Cyclists
- People eating a high carbohydrate diet could be fat adapted.
- Olympic class elite cyclists in Austin, Texas were burning 1.2 grams of fat per minute in 1986.
- Tour de France cyclists are likely fat adapted due to their long cycles.
- Runners are less likely to be fat adapted than cyclists due to differences in training.
Outpacing Dietary Substrate During Exercise
In this section, the speaker discusses how athletes can outpace their dietary substrate during exercise and become adapted depending on which type of exercise they do. He also talks about how power output differs between cycling and running.
Outpacing Dietary Substrate During Exercise
- Athletes can outpace their dietary substrate during exercise and become adapted.
- Cyclists can produce 350 watts of power continuously, while runners have lower power output.
- Elite athletes such as Dave Scott and Paula Newby-Fraser have reported improved performance on low-carb diets.
Female Athletes and Biochemical Principles
In this section, the speaker discusses whether the same biochemical principles apply to female athletes as they do to male athletes.
Women's Endurance
- In the 1970s, a German doctor came up with a theory that women would outrun men because they burn more fat when running.
- The speaker believes that there is no reason why women's muscles would metabolize differently than men's muscles in terms of energy metabolism.
- Therefore, the speaker thinks that the same biochemical principles apply to both sexes.
Low-Carb Diet and Diabetes
- The speaker developed type 2 diabetes as a result of following a high-carb diet while running marathons.
- A study showed that 30 recreational athletes became pre-diabetic on a low-carbohydrate diet.
- However, those who burned the most fat had improved glucose control when on a high-fat diet.
- This was the first study linking fat oxidation and muscle with more resistance to type 2 diabetes or pre-diabetes.
Carbohydrate Intake for Runners
- The key to being healthy for metabolic health is titrating how much carbohydrates are in your diet and how much you can cope with.
- Thirty percent of runners eating this high carbohydrate diet in their 30s or 40s are likely pre-diabetic if tested properly.
- People who finish marathons in six hours may be carrying extra fat but believe they are healthy because they run.
The Importance of Carbohydrates in Diet
In this section, the speakers discuss the importance of carbohydrates in a diet and how they can affect blood sugar levels.
Understanding Carbohydrates
- There is a distinction between all carbohydrates and ultra-processed carbohydrates.
- Consuming processed carbohydrates before and after workouts can lead to chaotic blood sugar dynamics.
- It is important to pick specific carbohydrates that are not an assault on the bloodstream, such as berries or sweet potatoes.
Exercise and Blood Sugar Dynamics
- Ultra processed foods are designed to be addictive, leading to obesity.
- Depending on how much one exercises, consuming carbohydrates may be fine as they will be burned off.
- Long periods of exercise can stabilize glucose levels and make the body feel better.
Personal Experience with Carbohydrate Intake
- The speaker recognized he was pre-diabetic despite being in good physical shape due to his carbohydrate intake.
- The speaker has experimented with different diets, including ketogenic and balanced diets with carefully chosen carbohydrates.
- The speaker noticed weight gain when he couldn't regulate his blood glucose levels.
Glucose Dynamics During Exercise
In this section, Dr. Peter Attia discusses the glucose dynamics during exercise and how it affects pre-diabetic individuals.
Glucose Spikes During High-Intensity Exercise
- Pre-diabetic individuals may experience a rise in glucose levels during high-intensity exercise.
- Even during prolonged endurance-type exercise, glucose levels can increase in pre-diabetic individuals.
- Although not serious, sustained high glucose levels with high insulin levels can be a marker of pre-diabetes.
- The best way to lower insulin apart from not eating carbs is through exercise.
Reduction of Glucose Spikes Through Diet
- A higher fat-based diet should reduce glucose spikes over time given the same intensity.
- Normalization of glucose levels was observed even during exercise with a greater return to normal on a low-carb diet.
Insulin Resistance and Hyperglycemia
- Elevated glucose from high-intensity exercise is different from elevated glucose from drinking soda due to different biochemical processes in the body.
- Hyperglycemia is more problematic than hypoglycemia for athletes who need to maintain their energy levels.
Fasted Exercise and Metabolic Fitness
In this section, the speakers discuss the benefits of fasted exercise in improving metabolic function and fitness.
Fasting and Exercise
- The speaker personally feels good when doing prolonged Zone 2 exercise fasted.
- Fasting is healthy, and combining it with exercise can have a double benefit in reversing metabolic syndrome.
- High carbohydrate diets are the greatest threat to the body, not fasting or starvation.
- The body can cope with fasting; the world record for fasting is 380 days.
Evolutionary Context for Low Carb Adaptation
In this section, the speakers discuss why low carb adaptation may be more efficient from an evolutionary perspective.
Efficient Fuel Substrate
- For each gram of fat, you get nine calories of energy compared to four calories per gram of carbohydrate.
- An average person carrying over a hundred thousand calories of fat energy versus only 30 to 40 thousand calories if they were carrying that same body weight in glucose or glycogen.
- Evolution adapted humans to eat high-fat high protein diets.
Evolutionary History of Human Diet
In this section, the speakers discuss how humans evolved to eat high-fat diets.
Human Diet Evolution
- Two papers published recently showed that elephants had a huge pad of fat below their foot bone which humans hunted for fat.
- Humans had cut marks on the bones of animals showing that they specifically went for the fat.
- Paranthropus, one of our predecessors, was killing rhinoceroses three million years ago.
The History of Carbohydrates in Human Diets
In this section, the speaker discusses how carbohydrates came into human diets and how they became a primary source of energy.
Carbohydrates as a Replacement for Fat Animals
- Humans started consuming carbohydrates 12,000 years ago with the Agricultural Revolution.
- This was because there were not enough fat animals on all continents to sustain human populations.
- As a result, humans had to find an alternative source of energy, which became cereals and grains.
Exponential Increase in Processed Sugar Consumption
- Over time, humans have exponentially increased their consumption of processed sugar and carbohydrates.
- In just 15 minutes, people can consume more sugar directly into their bloodstream than most predecessors would come across in months or years.
- This has put an enormous load on our systems and affected our health negatively.
Impact on Teeth Health
- Populations that converted to high processed foods destroyed their teeth and didn't have dentists to help them survive.
- If your diet kills your teeth, you're finished because you get brain abscesses and other complications.
Research Questions on Fuel Adaptation
In this section, the speaker talks about what he thinks researchers need to answer next regarding fuel adaptation.
Importance of Accepting Data
- The most important question is getting people to accept the data.
- To do that, we need lots of people who previously promoted high carb diets doing research and proving that they were wrong.
Industry Funding
- The problem is that the industry funds people to study carbohydrates, which is why carbohydrates are so dominant.
- The speaker was funded by the carbohydrate industry for 15-20 years and did fabulous studies, but they were all looking at carbohydrate metabolism.
Critical Low Carb Studies
- Only right at the end did they do some studies where they did low carb studies, and they were critical.
- These studies showed that if you had high muscle glycogen, you burn carbohydrates. If you have low muscle glycogen, you burn fat.
Impact on Runners' Health
- Runners are getting the wrong advice, and their health is being affected negatively.
- The speaker's health was affected as he became more diabetic or pre-diabetic as he ate more carbs.
The Role of Carbs and Fat in Athletic Performance
In this section, the speaker discusses the role of carbohydrates and fat in athletic performance. He talks about a study he would like to conduct to see what happens when high carb athletes run out of glycogen after three hours of exercise.
High Carb vs. High Fat Diets
- Burning fat from the start allows athletes to go for 3-5 hours without running out of energy, while burning carbs requires slowing down or stopping.
- The speaker believes that diet does not play a significant role in athletic performance.
- A cycling exercise for up to eight hours showed evidence that the high-fat group performed better than the high-carb group.
Health Benefits of a High-Fat Diet
- The speaker believes that a high-fat diet is healthier than a high-carb diet because it reduces inflammation and lowers the risk of injury.
- An athlete who ran a 100-mile race completely fasted showed with glucose data that his body was able to manage the situation effectively by burning fat.
Measuring Molecules for Metabolic Health and Performance
In this section, the speaker talks about measuring molecules in addition to continuous glucose data to demonstrate metabolic conditions for best metabolic health and how they affect performance.
Key Molecules for Measuring Metabolic Health
- Fat oxidation is an essential factor in measuring metabolic health as it indicates how much fat an individual can oxidize.
- There is no single molecule as helpful as glucose at present, but measuring glucose and fat oxidation simultaneously would be helpful in classifying people into different levels of carbohydrate and fat oxidation during exercise.
- The speaker predicts that carb-adapted athletes will hit a plateau when they run out of glycogen after 4-5 hours, while fat-adapted athletes will continue to burn fat effectively.
Fat Conversion and Exercise
In this section, the speaker discusses how during a hundred mile race, athletes have to become hypoglycemic. If they don't, it's because they're converting fat into glucose blood glucose.
Fat Conversion and Exercise
- During a hundred mile race, athletes have to become hypoglycemic.
- Athletes convert fat into glucose blood glucose if they don't become hypoglycemic.
- The topic of research on fat conversion is interesting.
- The speaker appreciates the opportunity to discuss their work and push forward on science.
- There may be resistance to accepting that carbohydrates are not as important as previously thought.
- Athletes do not need to eat high amounts of carbohydrates and doing so can harm their health in the long term.